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Depression
 
# 211 : Wednesday 16-11-2016 @ 23:07
 
 
Very impressed with Al Porter coming out tonight as being on medication for his chemical imbalance which caused him depression and how his tablets have helped, he explained his condition very well.
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# 212 : Thursday 17-11-2016 @ 07:45
 
 
It's great when public figures talk about it, it really needs to loose its stigma.

I spent most of 2016 depressed, it was a horrible year!
Reply
 
# 213 : Saturday 26-11-2016 @ 19:08
 
 
Magic mushrooms lift severe depression in trial

A hallucinogenic chemical found in magic mushrooms has successfully lifted severe depression in previously untreatable patients.

Scientists at Imperial College London induced intense psychedelic trips in 12 people using high doses of the banned substance psilocybin.

A week after the experience all the volunteers were depression-free, and three months later five still had no symptoms of the condition.

Published in the Lancet Psychiatry Journal, the study welcomes the results as “promising, but not completely compelling".

Its authors are now seeking further funding from the Medical Research Council and other bodies to carry out fuller trials.

They conceded, however, that the use of a placebo control, a crucial component of thorough clinical trials, would be difficult as it would be obvious who was having a hallucinogenic experience and who was not.

The psilocybin is believed to cause relief from depression by targeting receptors in the brain and disrupting the Default Mode Network, which is responsible for sense of self and is overactive in depressed people.

However, the scientists did not rule out that the psychedelic trip could have caused an “awakening”, of the kind achieved by spiritual teaching, which also helped lift the depression.

An estimated 350 million people worldwide are affected by the disease and the annual cost to the economy in England is thought to be around £7.5 billion, according to government figures.

About one in ten patients are resistant to treatment.

Despite the promising results, the researchers urged people not to try magic mushrooms themselves as a cure for depression.

Lead author Dr Robin Carhart-Harris, said: “Psychedelic drugs have potent psychological effects and are only given in our research when appropriate safeguards are in place, such as careful screening and professional therapeutic support.

“I wouldn’t want members of the public thinking they can treat their own depressions by picking their own magic mushrooms.

“That kind of approach could be risky.”

The volunteers in the trial had the psilocybin administered orally in capsules and were then closely monitored.

more
http://www.telegraph.co.uk/science/2016/05/17/magic-mushrooms-lif etc ...


(I'm not sure it helps that one of the scientists doing the research is a Nutt)
Reply
 
# 214 : Saturday 26-11-2016 @ 19:24
 
 
I wonder, is there anything contained in food causing it and has it been checked?
Reply
 
# 215 : Sunday 27-11-2016 @ 01:42
 
 
Someone said :
I wonder, is there anything contained in food causing it and has it been checked?

Like what?
Reply
 
# 216 : Sunday 27-11-2016 @ 02:12
 
 
Someone said :
Magic mushrooms lift severe depression in trial

A hallucinogenic chemical found in magic mushrooms has successfully lifted severe depression in previously untreatable patients.

Scientists at Imperial College London induced intense psychedelic trips in 12 people using high doses of the banned substance psilocybin.

A week after the experience all the volunteers were depression-free, and three months later five still had no symptoms of the condition.

Published in the Lancet Psychiatry Journal, the study welcomes the results as “promising, but not completely compelling".

Its authors are now seeking further funding from the Medical Research Council and other bodies to carry out fuller trials.

They conceded, however, that the use of a placebo control, a crucial component of thorough clinical trials, would be difficult as it would be obvious who was having a hallucinogenic experience and who was not.

The psilocybin is believed to cause relief from depression by targeting receptors in the brain and disrupting the Default Mode Network, which is responsible for sense of self and is overactive in depressed people.

However, the scientists did not rule out that the psychedelic trip could have caused an “awakening”, of the kind achieved by spiritual teaching, which also helped lift the depression.

An estimated 350 million people worldwide are affected by the disease and the annual cost to the economy in England is thought to be around £7.5 billion, according to government figures.

About one in ten patients are resistant to treatment.

Despite the promising results, the researchers urged people not to try magic mushrooms themselves as a cure for depression.

Lead author Dr Robin Carhart-Harris, said: “Psychedelic drugs have potent psychological effects and are only given in our research when appropriate safeguards are in place, such as careful screening and professional therapeutic support.

“I wouldn’t want members of the public thinking they can treat their own depressions by picking their own magic mushrooms.

“That kind of approach could be risky.”

The volunteers in the trial had the psilocybin administered orally in capsules and were then closely monitored.

more
http://www.telegraph.co.uk/science/2016/05/17/magic-mushrooms-lif etc ...


(I'm not sure it helps that one of the scientists doing the research is a Nutt)

Legalise the happy drugs and stop the bloody nonsense, crack down on crack and smack and make the World a better, saner place.
Reply
 
# 217 : Sunday 27-11-2016 @ 08:50
 
 
Someone said :

Like what?

Processed foods, flavourings and preservatives etc. Are any of these additives, affecting the brain and since mankind started producing food from the factories, we've had a number of illnesses becoming epidemic.
Reply
 
# 218 : Sunday 27-11-2016 @ 16:47
 
 
Someone said :
Magic mushrooms lift severe depression in trial

A hallucinogenic chemical found in magic mushrooms has successfully lifted severe depression in previously untreatable patients.

Scientists at Imperial College London induced intense psychedelic trips in 12 people using high doses of the banned substance psilocybin.

A week after the experience all the volunteers were depression-free, and three months later five still had no symptoms of the condition.

Published in the Lancet Psychiatry Journal, the study welcomes the results as “promising, but not completely compelling".

Its authors are now seeking further funding from the Medical Research Council and other bodies to carry out fuller trials.

They conceded, however, that the use of a placebo control, a crucial component of thorough clinical trials, would be difficult as it would be obvious who was having a hallucinogenic experience and who was not.

The psilocybin is believed to cause relief from depression by targeting receptors in the brain and disrupting the Default Mode Network, which is responsible for sense of self and is overactive in depressed people.

However, the scientists did not rule out that the psychedelic trip could have caused an “awakening”, of the kind achieved by spiritual teaching, which also helped lift the depression.

An estimated 350 million people worldwide are affected by the disease and the annual cost to the economy in England is thought to be around £7.5 billion, according to government figures.

About one in ten patients are resistant to treatment.

Despite the promising results, the researchers urged people not to try magic mushrooms themselves as a cure for depression.

Lead author Dr Robin Carhart-Harris, said: “Psychedelic drugs have potent psychological effects and are only given in our research when appropriate safeguards are in place, such as careful screening and professional therapeutic support.

“I wouldn’t want members of the public thinking they can treat their own depressions by picking their own magic mushrooms.

“That kind of approach could be risky.”

The volunteers in the trial had the psilocybin administered orally in capsules and were then closely monitored.

more
http://www.telegraph.co.uk/science/2016/05/17/magic-mushrooms-lif etc ...


(I'm not sure it helps that one of the scientists doing the research is a Nutt)

I'm a bit fed up of hearing of these trials. These have been going on for years with no proper follow up to phychosis.
Despite cynicism of the pharmaceutical industry those that respond to the dopamine chemical being regulated with a controlled pill should stick to that. A pill that titrates the release of dopamine to that persons individual brain chemistry will fare better than a blanket lift of dopamine. Unlike SSRIs that work on the Serotonin they can only up the level. Too much of something can result in depression just as much.

Says me who has had a rare weekend off and has absolutely wasted it by smoking my brains out after struggling being off it for quite a while. Dissappointed.Com
Reply
 
# 219 : Sunday 27-11-2016 @ 16:59
 
 
Someone said :

Processed foods, flavourings and preservatives etc. Are any of these additives, affecting the brain and since mankind started producing food from the factories, we've had a number of illnesses becoming epidemic.

Thats part of the problem allright. One factor in a huge cluster.
Reply
 
# 220 : Sunday 27-11-2016 @ 18:19
 
 
How is that part of the problem? Has there been any studies linking depression to additives or processed foods?
Reply
 
# 221 : Sunday 27-11-2016 @ 19:42
 
 
Someone said :
How is that part of the problem? Has there been any studies linking depression to additives or processed foods?

http://www.sciencedaily.com/releases/2012/03/120330081352.htm
Reply
 
# 222 : Sunday 27-11-2016 @ 19:45
 
 
That's what I'm asking. Why say additives cause depression without a shred of evidence that they do?
Reply
 
# 223 : Sunday 27-11-2016 @ 19:46
 
 
Someone said :
That's what I'm asking. Why say additives cause depression without a shred of evidence that they do?

I'm not saying, just listing ingredients and asking if they play a part?
Reply
 
# 224 : Sunday 27-11-2016 @ 20:16
 
 
Of course whats in our food contributes to our mood. Anyone who suffers badly will recognise a sugar high and the inevitable crash after. Just one example.
Reply
 
# 225 : Sunday 27-11-2016 @ 20:42
 
 
Sugar high is a myth http://www.webmd.com/parenting/features/busting-sugar-hyperactivi etc ...


There's absolutely no proof additives cause depression or affect mood in anyway.
Reply
 
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